Personal Profile
Dr. Gu's research focuses on Position Emission Tomography (PET) imaging technology, pushing for the greatest possible spatial resolution and sensitivity of PET imaging through the development of innovative and fundamental technologies to enhance key parameters such as time-of-flight (TOF), depth-of-interaction (DOI), et al. With multiple core detector technologies developed as the foundation, three categories of PET prototype systems are being developed in Gu's lab: preclinical (small animal), human brain-dedicated, and human organ-targeted instruments, with the goal of providing technology leading imaging tools for biomedical and clinical applications.
Education & Experience
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2020 - Present, Institute of Biomedical Engineering, Shenzhen Bay Laboratory, Junior Principal Investigator
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2017 - 2020, Chatziioannou Lab, University of California, Los Angeles, Project scientist
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2015 - 2017, Chatziioannou Lab, University of California, Los Angeles, Associate project scientist
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2015 - 2020, Sofie Biosciences, Culver City, CA, Senior imaging scientist
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2014 - 2015, Chatziioannou Lab, University of California, Los Angeles, Postdoctoral researcher
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2009 - 2014, Chatziioannou Lab, University of California, Los Angeles, Graduate student researcher, research advisor: Arion Xenofon Chatziioannou, Ph.D.
Research Interests
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Positron Emission Tomography (PET) imaging technology
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Development of high-resolution, high-effciency PET detectors
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Time of Flight (TOF) and Depth of Interaction (DOI) technologies
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Development of preclinical (small animal), brain-dedicated, and organ-specific PET prototypes systems
Fundings
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National Key Research and Development Program of China (Young Scientists Project), 2023-2026.
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National Natural Science Foundation of China (General Program), 2023-2026 .
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Guangdong Basic and Applied Basic Research Foundation (General Program), 2023-2025.
Representative Publications
(*: Corresponding author, #: The first two authors contributed equally to this paper)
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Niu M, Kuang Z, Wang X, Ren N, Sang Z, Sun T, Liu Z, Hu Z, Gu Z*, Y Yang, 2024, Comparison of timing measurement methods of dual-ended readout scintillator array PET detectors, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 8, PP. 607-617.
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He W, Zhao Y, Zeng H, Huang W, Yang H, Zhao X, Wang Q, Wang L, Niu M, Zhang L, Ren Q, Gu Z*, 2024, Design and characterization of a hybrid PET detector with DOI capability, Medical Physics.
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He W, Zhao Y, Huang W, Zhao X, Niu M, Yang H, Zhang L, Ren Q, Gu Z*, 2024, A multi-resolution TOF-DOI detector for human brain dedicated PET scanner, Physics in medicine and biology, 69 (2), 025023.
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He W, Zhao Y, Zhao X, Huang W, Zhang L, Prout D, Chatziioannou A, Ren Q, Gu Z*, 2023, A CNN-based four-layer DOI encoding detector using LYSO and BGO scintillators for small animal PET imaging, Physics in Medicine and Biology , 68 095021.
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Prout D L#, Gu Z#, Shustef M and Chatziioannou A F, 2020 A digital phoswich detector using time-over-threshold for depth of interaction in PET, Physics in Medicine and Biology, 65, (24).
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Gu Z, Taschereau R, Vu N, Prout D L, Lee J and Chatziioannou A F, 2020 Performance evaluation of HiPET, a high sensitivity and high resolution preclinical PET tomograph, Physics in Medicine and Biology, 65 , (4).
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Gu Z, Taschereau R, Vu N, Prout D L, Silverman R W, Lee J and Chatziioannou A F, 2019 Performance evaluation of G8, a high sensitivity benchtop preclinical PET/CT tomograph, The Journal of Nuclear Medicine, vol. 60, pp. 142-9.
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Gu Z, Prout D L, Taschereau R, Bai B and Chatziioannou A F, 2016 A New Pulse Pileup Rejection Method Based on Position Shift Identification, IEEE Transactions on Nuclear Science, vol. 63, pp. 22-9.
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Gu Z, Prout D L, Silverman R W, Herman H, Dooraghi A and Chatziioannou A F, 2015 A DOI Detector With Crystal Scatter Identification Capability for High Sensitivity and High Spatial Resolution PET Imaging IEEE Transactions on Nuclear Science vol. 62, pp. 740-7.
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Gu Z, Q Bao, Taschereau R, Wang H, Bai B and Chatziioannou A F 2014 Optimization of the energy window for PETbox4, a preclinical PET tomograph with a small inner diameter IEEE Transactions on Nuclear Science vol. 61, pp. 1164-1173.
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Gu Z, Taschereau R, Vu N T, Wang H, Prout D L, Silverman R W, Bai B, Stout D B, Phelps M E and Chatziioannou A F 2013 NEMA NU-4 performance evaluation of PETbox4, a high sensitivity dedicated PET preclinical tomograph Physics in Medicine and Biology 58 3791-814.
Additional Information
